Improving pain management for veterans with severe kidney disease

Optimizing Pain Management in End-Stage Renal Disease Among Veterans (OPERA-Vets):Balancing Benefits and Harms of Opioids

NIH-funded research VA Boston Health Care System · NIH-10923830

This study looks at how new rules about prescribing opioids impact veterans with severe kidney disease who are dealing with pain, and it aims to find safer ways to help them manage their pain without increasing risks.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA Boston Health Care System NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10923830 on NIH RePORTER

What this research studies

This research investigates how recent opioid prescribing policies affect veterans suffering from end-stage renal disease (ESRD). It focuses on balancing the benefits and risks of opioid use, particularly for veterans who experience significant pain but are at high risk for opioid-related complications. The study aims to understand the implications of these policies on pain management and explores alternative pain relief strategies that may be more suitable for this vulnerable population. By analyzing data from veterans receiving dialysis, the research seeks to identify effective approaches to optimize pain control while minimizing risks.

Who could benefit from this research

Good fit: Ideal candidates for this research are veterans diagnosed with end-stage renal disease who experience chronic pain.

Not a fit: Patients who do not have end-stage renal disease or those who are not veterans may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management strategies for veterans with end-stage renal disease, enhancing their quality of life.

How similar studies have performed: Previous research has shown that addressing opioid safety in chronic pain populations can lead to better pain management outcomes, suggesting that this approach may also be effective for veterans with ESRD.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.