Improving pain management for children on mechanical ventilation
Optimizing Pain Treatment In Children On Mechanical ventilation (OPTICOM)
['FUNDING_U01'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-10990648
This study is looking at how to help manage pain better for kids on breathing machines by testing if adding non-opioid medicines like acetaminophen and ketorolac can help them feel more comfortable while using fewer stronger painkillers.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10990648 on ClinicalTrials.gov |
What this research studies
This research investigates how to better manage pain in children who require mechanical ventilation due to acute respiratory failure. It aims to find out if adding non-opioid medications like acetaminophen and ketorolac can improve pain control while reducing the need for opioids. The study will involve 644 children across 14 pediatric intensive care units, where participants will be randomly assigned to receive either the non-opioid treatments or a placebo. By focusing on a protocolized approach to pain management, the research seeks to enhance the overall care and recovery of these vulnerable patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are experiencing acute respiratory failure and require mechanical ventilation.
Not a fit: Patients who are not undergoing mechanical ventilation or are outside the age range of 0-11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved pain control and reduced opioid use in children undergoing mechanical ventilation.
How similar studies have performed: Previous studies have indicated that non-opioid adjuvant therapies can be effective in managing pain, but this specific approach in the pediatric population on mechanical ventilation is novel.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TRAUBE, CHANI — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: TRAUBE, CHANI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.