NIH-funded research R01 grant

Improving pain management for breast cancer survivors

Official title: Enhanced Pain Coping in Cancer (EPIC)

Funded at Sloan-Kettering Inst Can Research · NIH-10976050 · Data updated 2026-11-12

This study is looking at a mindfulness program called Mindfulness-Oriented Recovery Enhancement (MORE) to see if it can help breast cancer survivors who are dealing with pain from their treatment, making it easier for them to manage their pain and feel better overall.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSloan-Kettering Inst Can Research
NIH-funded
Lab location1 site (New York, United States)
Project startJuly 1, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$732,536
NIH project number1R01CA285746-01A1
Project IDNIH-10976050 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are breast cancer survivors who are experiencing chronic pain related to aromatase inhibitors.

Less likely to help

Patients who are not breast cancer survivors or those not experiencing chronic pain may not benefit from this research.

What this research studies

This research investigates a mindfulness-based intervention called Mindfulness-Oriented Recovery Enhancement (MORE) to help breast cancer survivors cope with chronic pain, specifically focusing on those experiencing aromatase inhibitor-associated arthralgia. The study aims to assess the effectiveness of MORE in reducing pain and psychological distress through techniques that promote mindfulness, cognitive reappraisal, and savoring experiences. Participants will engage in a randomized controlled trial to evaluate the intervention's impact on their quality of life and pain management. By addressing both physical and emotional aspects of pain, this research seeks to provide a holistic approach to improving the well-being of cancer survivors.

Why it matters

Potential benefit: If successful, this research could lead to more effective pain management strategies for breast cancer survivors, enhancing their quality of life.

How similar studies have gone: Previous research has shown that mindfulness-based interventions can effectively reduce pain in non-cancer populations, suggesting potential for success in this novel application.

Where this research is happening

  • Sloan-Kettering Inst Can Research
    New York, United States
    Active

Researchers

  • Principal investigator: Mao, Jun J — Sloan-Kettering Inst Can Research
  • Study coordinator: Mao, Jun J

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.