NIH-funded research NIH-funded research

Improving pain management and opioid safety using data-driven guidelines

Official title: Improving pain management and opioid safety through a systemwide, data driven evaluation of the CDC opioid prescribing guideline best practices and the use of Clinical Decision Support

Funded at University of Colorado Denver · NIH-11137512 · Data updated 2026-11-12

This study is looking to improve how doctors manage pain and safely prescribe opioids by using new guidelines and tools in their electronic health records, so patients can get better pain relief and overall health care.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startSeptember 30, 2022
Project endAugust 31, 2027
Funding year2024
Award (this year)$2,814,796
NIH project number4R33DA057610-02
Project IDNIH-11137512 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include patients who are prescribed opioids for chronic pain management.

Less likely to help

Patients who do not require opioid medications for pain management may not benefit from this research.

What this research studies

This research aims to enhance pain management while ensuring the safe prescription of opioid medications. It focuses on implementing updated CDC opioid prescribing guidelines through a system that utilizes Clinical Decision Support (CDS) embedded in electronic health records. By conducting a hybrid effectiveness-implementation trial, the research will evaluate how well these guidelines can be integrated into clinical practice and their impact on patient outcomes, such as pain control and overall health. The study will also explore the factors that affect the successful adoption of these practices by healthcare providers.

Why it matters

Potential benefit: If successful, this research could lead to safer opioid prescribing practices and improved pain management for patients.

How similar studies have gone: Previous research has shown that implementing evidence-based guidelines can lead to improvements in patient outcomes, suggesting that this approach may be effective.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Hoppe, Jason — University of Colorado Denver
  • Study coordinator: Hoppe, Jason

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.