NIH-funded research U01 cooperative agreement

Improving pain management after laparoscopic surgery to reduce opioid use

Official title: Managing Perioperative Pain with Abdominal Laparoscopic Surgery: A Collaborative to Develop, Disseminate, and Evaluate Evidence-Based Practices (M-PALS Collaborative)

Funded at University of Minnesota · NIH-10907265 · Data updated 2026-11-12

This study is working on new guidelines to help doctors manage pain after laparoscopic surgeries, so patients can feel better with less need for strong painkillers like opioids.

More Laparoscopic Surgery research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Minnesota
NIH-funded
Lab location1 site (Minneapolis, United States)
Project startSeptember 25, 2023
Project endSeptember 24, 2026
Funding year2023
Award (this year)$1,999,999
NIH project number1U01FD008147-01
Project IDNIH-10907265 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients scheduled for abdominal laparoscopic surgeries who are opioid naive or have limited prior exposure to opioids.

Less likely to help

Patients who are not undergoing abdominal laparoscopic surgeries or those with chronic pain conditions requiring ongoing opioid management may not benefit from this research.

What this research studies

This research focuses on developing and implementing evidence-based guidelines for managing pain after abdominal laparoscopic surgeries, which are increasingly common. The project aims to create a clinical practice guideline (CPG) by collaborating with experts and stakeholders, ensuring that the guidelines are applicable across various surgical settings. By evaluating the effectiveness of these guidelines in real-world practice, the research seeks to enhance pain management while minimizing the reliance on prescription opioids, thereby addressing the public health crisis of opioid use disorder.

Why it matters

Potential benefit: If successful, this research could lead to better pain management strategies for patients undergoing laparoscopic surgery, reducing their need for opioids and improving overall satisfaction.

How similar studies have gone: Other research has shown success in developing pain management protocols that reduce opioid use, indicating that this approach has potential for positive outcomes.

Where this research is happening

  • University of Minnesota
    Minneapolis, United States
    Active

Researchers

  • Principal investigator: Southwell, Bronwyn J — University of Minnesota
  • Study coordinator: Southwell, Bronwyn J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.