Improving Outcomes for Veterans with Substance Use and PTSD by Treating Sleep Apnea

Examining Early Intervention Obstructive Sleep Apnea Treatment on Long-Term Outcomes in Veterans with SUD/PTSD in a Residential Treatment Program

NIH-funded research VA San Diego Healthcare System · NIH-11191384

This work looks at how treating sleep apnea early might help Veterans who are in residential programs for substance use disorder and PTSD.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA San Diego Healthcare System NIH-funded
Lab location1 site (San Diego, United States)
Project IDNIH-11191384 on NIH RePORTER

What this research studies

Many Veterans dealing with both substance use disorder (SUD) and posttraumatic stress disorder (PTSD) also have obstructive sleep apnea (OSA), a condition where breathing repeatedly stops and starts during sleep. Untreated OSA can make SUD and PTSD symptoms worse, affecting overall well-being and increasing the risk of relapse or suicidal thoughts. While positive airway pressure (PAP) is a proven treatment for OSA, it's not usually part of SUD or PTSD care. This research aims to understand if providing early OSA treatment can lead to better long-term recovery for these Veterans.

Who could benefit from this research

Good fit: Ideal candidates for this type of research would be Veterans in residential treatment programs who have both substance use disorder and PTSD, and also suffer from obstructive sleep apnea.

Not a fit: Patients who do not have co-occurring substance use disorder, PTSD, and obstructive sleep apnea, or who are not in a residential treatment setting, may not directly benefit from this specific approach.

Why it matters

Potential benefit: If successful, this work could lead to better treatment strategies for Veterans with co-occurring SUD and PTSD, improving their recovery and quality of life.

How similar studies have performed: While positive airway pressure (PAP) is a well-established and effective treatment for obstructive sleep apnea, its integration and impact on co-occurring substance use disorder and PTSD in Veterans is a less explored area.

Where this research is happening

San Diego, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.