Improving outcomes for patients with knee osteoarthritis pain

A sequenced-strategy for improving outcomes in patients with knee osteoarthritis pain

['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-10700013

This study is looking at different ways to help older adults with knee osteoarthritis feel better, by comparing online therapy and certain medications to regular care, and if those don’t work, it will also check out some non-surgical options to improve their pain and daily life.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorJOHNS HOPKINS UNIVERSITY (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-10700013 on ClinicalTrials.gov

What this research studies

This research investigates effective treatments for knee osteoarthritis (KOA), a condition that causes chronic pain and disability in older adults. It aims to compare the effectiveness of behavioral therapies, like online cognitive behavioral therapy, and non-opioid medications against standard care. If patients do not respond to these initial treatments, the study will also explore the benefits of nonsurgical procedures. The goal is to provide better pain management options and improve the quality of life for those suffering from KOA.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults suffering from knee osteoarthritis pain who are seeking non-surgical treatment options.

Not a fit: Patients with knee osteoarthritis who have already undergone surgical interventions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective pain management strategies for patients with knee osteoarthritis, reducing reliance on opioids.

How similar studies have performed: Previous research has shown promise in using behavioral therapies and non-opioid treatments for managing chronic pain, indicating that this approach could be effective.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.