Improving outcomes for older adults after heart attacks
Official title: Effectiveness of Strategies to Improve Outcomes after Hospitalization for Acute Myocardial Infarction in Older Adults
Funded at Yale University · NIH-10794248 · Data updated 2026-11-12
This study is looking at how to help older adults, especially those 75 and up, recover better after a heart attack by understanding their specific challenges and finding ways to improve their care after leaving the hospital.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | March 1, 2022 |
| Project end | February 28, 2026 |
| Funding year | 2024 |
| Award (this year) | $530,760 |
| NIH project number | 5R01HL160822-03 |
| Project ID | NIH-10794248 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults aged 75 and above who have been hospitalized for acute myocardial infarction.
✕Less likely to help
Patients younger than 75 or those who have not experienced an acute myocardial infarction may not benefit from this research.
What this research studies
This research investigates how to enhance recovery and outcomes for older adults who have experienced acute myocardial infarction (heart attacks). It focuses on understanding the unique challenges faced by patients aged 75 and older, including their functional impairments and cognitive issues. By analyzing data from over 3,000 older patients, the study aims to identify which factors can predict risks after hospital discharge and how tailored post-hospital care can be implemented effectively. The goal is to develop evidence-based strategies that healthcare systems can use to improve care for this vulnerable population.
Why it matters
Potential benefit: If successful, this research could lead to better recovery strategies for older adults after heart attacks, potentially reducing mortality and improving quality of life.
How similar studies have gone: Previous research has shown that targeted interventions for older adults post-hospitalization can improve outcomes, suggesting that this approach has potential for success.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Chaudhry, Sarwat I — Yale University
- Study coordinator: Chaudhry, Sarwat I
Related research
Other NIH-funded projects on the same topics.
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Targeted nanotherapy to calm inflammation, grow new blood vessels, and prevent scarring after a heart attack
A new treatment approach uses engineered secretions from immune cells delivered early after a heart attack to reduce inflammation, promote blood vessel growth, and limit scarring to protect heart function.
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A new AI-based approach uses everyday wearable sensors to turn simple PPG signals into multi-lead ECG data to monitor for heart attacks in real time, even outside the clinic.
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Extreme heat and heart attack risk: who is most at risk and why
High heat and air pollution may raise the risk of heart attacks, and this project looks at who is most affected.
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MMP-responsive biomaterials to treat a heart attack
A heart-attack treatment using smart materials that release healing therapies right where the heart was damaged, aimed at people who’ve had a heart attack.
-
Nanoparticle therapy to reduce inflammation and scarring after a heart attack
Tiny engineered nanoparticles will deliver anti-inflammatory and anti-scarring substances to the heart soon after a heart attack to help people recover better.
-
Using ultrasound images and AI to better describe and predict heart attacks
This project uses routine heart ultrasound images plus AI to create detailed profiles that help predict outcomes for people hospitalized with acute heart attacks.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.