Improving outcomes for cancer survivors with testosterone therapy
Improving Patient-Important Outcomes with Testosterone Replacement in Hypogonadal Men with a Prior History of Cancer
This study is looking at whether testosterone replacement therapy can help young male cancer survivors who feel tired and have other health issues due to low testosterone levels, by checking if it improves their energy, sexual health, quality of life, and physical strength.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Seattle Inst for Biomedical/clinical Res NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11143700 on NIH RePORTER |
What this research studies
This research investigates the effects of testosterone replacement therapy on fatigue and other important health outcomes in young male cancer survivors who experience testosterone deficiency. The study will utilize a double-blind, randomized, placebo-controlled trial design, meaning that neither the participants nor the researchers will know who receives the actual treatment versus a placebo. Participants will be monitored for improvements in fatigue, sexual function, quality of life, body composition, muscle strength, and physical activity levels. The goal is to determine if testosterone therapy can alleviate debilitating symptoms that persist after cancer treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are young male cancer survivors who report fatigue and have been diagnosed with testosterone deficiency.
Not a fit: Patients who are not male cancer survivors or those who do not have testosterone deficiency may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life for cancer survivors suffering from fatigue and related symptoms.
How similar studies have performed: Previous trials have shown that testosterone replacement therapy can improve fatigue and related symptoms in non-cancer populations, suggesting potential for success in this novel application.
Where this research is happening
Seattle, United States
- Seattle Inst for Biomedical/clinical Res — Seattle, United States (Active)
Researchers
- Principal investigator: Garcia, Jose M. — Seattle Inst for Biomedical/clinical Res
- Study coordinator: Garcia, Jose M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.