Improving outcomes for breast cancer survivors through exercise and weight management
Official title: Taking AIM at Breast Cancer: Targeting Adiposity and Inflammation with Movement to Improve Prognosis in Breast Cancer Survivors
Funded at Dana-Farber Cancer Inst · NIH-10686204 · Data updated 2026-11-12
This study is looking at how exercise can help lower inflammation from obesity in women who have survived breast cancer after menopause, with the goal of finding the best types of workouts to improve their health and reduce the chances of cancer coming back.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dana-Farber Cancer Inst NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2018 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $610,690 |
| NIH project number | 5R01CA214385-06 |
| Project ID | NIH-10686204 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are postmenopausal women who are breast cancer survivors and are classified as obese.
✕Less likely to help
Patients who are not postmenopausal or do not have a history of breast cancer may not benefit from this research.
What this research studies
This research focuses on how exercise can help reduce chronic inflammation caused by obesity in postmenopausal breast cancer survivors. It investigates the relationship between white adipose tissue, inflammation, and cancer prognosis, aiming to identify effective forms of exercise that can improve health outcomes. By targeting the inflammation linked to excess fat, the study seeks to enhance the overall survival rates and reduce recurrence of breast cancer in this population. Participants may engage in tailored exercise programs designed to mitigate the effects of obesity on cancer progression.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and quality of life for breast cancer survivors dealing with obesity.
How similar studies have gone: Previous research has shown that exercise can positively impact inflammation and obesity, suggesting potential success for this approach.
Where this research is happening
-
Dana-Farber Cancer Inst
Boston, United States Active
Researchers
- Principal investigator: Dieli-Conwright, Christina — Dana-Farber Cancer Inst
- Study coordinator: Dieli-Conwright, Christina
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.