Improving outcomes after ischemic stroke using advanced testing methods
Official title: The NIH SPAN Coordinating Center
Funded at University of Southern California · NIH-10993647 · Data updated 2026-11-12
This study is working on new ways to help people recover better after a stroke by testing promising treatments in animals, including those with common health issues, to find out what works best for stroke patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | January 1, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $879,383 |
| NIH project number | 5U24NS130600-03 |
| Project ID | NIH-10993647 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced ischemic stroke or are at high risk for stroke due to conditions like hypertension or diabetes.
✕Less likely to help
Patients who have not experienced a stroke or do not have risk factors for stroke may not benefit from this research.
What this research studies
This research focuses on developing and implementing a secure system to test new interventions aimed at improving recovery after ischemic stroke. The Stroke Preclinical Assessment Network (SPAN) will evaluate promising treatments in animal models, ensuring a diverse representation of subjects, including those with common health issues like aging and hypertension. The study employs innovative methods for tracking and assessing treatment effects, including blinded evaluations and centralized assessments to minimize bias. By refining these testing processes, the research aims to identify effective therapies that could eventually benefit stroke patients.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve recovery outcomes for stroke patients.
How similar studies have gone: Previous research has shown promise in using adaptive testing methods for stroke interventions, indicating a potential for success in this novel approach.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Lyden, Patrick D — University of Southern California
- Study coordinator: Lyden, Patrick D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.