Improving oral drug delivery using polymer nanoparticles
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['FUNDING_R01'] · UNIVERSITY OF ALABAMA IN TUSCALOOSA · NIH-11093284
This study is exploring new ways to help medicines work better when taken by mouth, using tiny particles made from special materials that can help drugs get into your body more effectively, and it's designed for anyone interested in improving how medications are delivered.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ALABAMA IN TUSCALOOSA (nih funded) |
| Locations | 1 site (TUSCALOOSA, UNITED STATES) |
| Trial ID | NIH-11093284 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the delivery of pharmaceutical drugs through the use of polymer nanoparticles that can be administered orally. The project aims to address two main challenges: the need for versatile polymer structures for customized drug delivery and the development of predictive tools for understanding how these nanoparticles behave in the body. By synthesizing specialized polyesters and creating mathematical models, the research will investigate how these nanoparticles can effectively cross barriers in the body, such as the gut-blood barrier. This work involves a combination of laboratory experiments and computational modeling to provide insights into how drugs are absorbed, distributed, metabolized, and eliminated.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who need medications that are currently difficult to deliver effectively through oral routes.
Not a fit: Patients who do not require oral medications or those with conditions that necessitate alternative delivery methods may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective oral drug delivery systems, improving treatment outcomes for patients requiring medication.
How similar studies have performed: While the use of polymer nanoparticles for drug delivery is a growing field, this specific approach combining advanced polymer synthesis with predictive modeling is relatively novel.
Where this research is happening
TUSCALOOSA, UNITED STATES
- UNIVERSITY OF ALABAMA IN TUSCALOOSA — TUSCALOOSA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAJETI, RAVIKUMAR N — UNIVERSITY OF ALABAMA IN TUSCALOOSA
- Study coordinator: MAJETI, RAVIKUMAR N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.