Improving online exercise programs for adults with knee replacements

Optimizing a Remote-based Physical Activity Intervention for Adults with Total Knee Replacement

['FUNDING_R01'] · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · NIH-10940877

This study is looking to improve an online exercise program called Energize! for adults who have had total knee replacement surgery, helping them get more active and stay healthy after their recovery.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA (nih funded)
Locations1 site (COLUMBIA, UNITED STATES)
Trial IDNIH-10940877 on ClinicalTrials.gov

What this research studies

This research aims to enhance a remote-based physical activity program specifically designed for adults who have undergone total knee replacement (TKR). It addresses the common issue of low physical activity levels in this population by utilizing a fully automated internet platform called Energize!, which allows participants to plan, report, and receive feedback on their exercise routines. The study will explore various enhancements to this program to determine the most effective components for increasing physical activity among participants who are at least 12 months post-surgery. By employing a structured optimization strategy, the research seeks to create a scalable solution that can be accessible to a wide audience.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have had a total knee replacement at least 12 months prior.

Not a fit: Patients who have not undergone knee replacement surgery or those who are unable to engage in physical activity due to other medical conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved physical activity levels and overall health outcomes for adults recovering from knee replacement surgery.

How similar studies have performed: Previous research has shown promise in using internet-based interventions for increasing physical activity, though this specific approach for TKR patients is relatively novel.

Where this research is happening

COLUMBIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.