Improving nutrition for very low birth weight infants to enhance their growth and brain development.

Improving growth and neurodevelopment of very low birth weight infants through precision nutrition: The Optimizing Nutrition and Milk (Opti-NuM) Project.

NIH-funded research Hospital for Sick Chldrn (Toronto) · NIH-10907605

This study is all about finding the best ways to feed babies who were born very small so they can grow strong and develop well, by looking at their unique needs and how things like family stress and genetics play a role in their nutrition.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHospital for Sick Chldrn (Toronto) NIH-funded
Lab location1 site (Toronto, Canada)
Project IDNIH-10907605 on NIH RePORTER

What this research studies

This research focuses on optimizing nutrition for infants born with very low birth weight (VLBW) to improve their growth and neurodevelopment. It aims to personalize human milk feeding strategies by understanding the specific nutritional needs of these infants, taking into account various factors such as parental stress and infant genetics. By analyzing the components of human milk and their effects on health outcomes, the project seeks to develop tailored feeding approaches that can better support the health of VLBW infants. The study will utilize established research networks to gather data and implement interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research are infants born with very low birth weight, typically weighing less than 1500 grams.

Not a fit: Patients who are not born with very low birth weight or those who do not require specialized nutritional interventions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved growth and neurodevelopmental outcomes for very low birth weight infants.

How similar studies have performed: Previous research has shown promise in using personalized nutrition approaches for improving health outcomes in vulnerable infant populations, indicating potential for success in this novel approach.

Where this research is happening

Toronto, Canada

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.