Improving NMR techniques for studying complex molecules
Integrated NMR for Complex Systems
['FUNDING_OTHER'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-11021094
This study is working on making it easier and faster for scientists to use a special technique called NMR spectroscopy to understand the structures of complex molecules like proteins, which could help improve treatments for diseases in the future.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-11021094 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the automation of Nuclear Magnetic Resonance (NMR) spectroscopy, which is crucial for determining the structures of complex molecules like proteins. The project aims to develop advanced algorithms and user-friendly interfaces that will streamline the process of analyzing NMR data, particularly for larger proteins and complex structures that are typically challenging to study. By automating various steps such as sample preparation, data processing, and signal identification, the research seeks to reduce the time and costs associated with NMR studies, making this powerful technique more accessible to researchers. Patients may benefit indirectly through advancements in understanding diseases at the molecular level, leading to better-targeted therapies.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with conditions that involve complex protein structures, such as certain genetic disorders or cancers.
Not a fit: Patients with conditions that do not involve protein structure abnormalities may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate molecular structure determination, potentially accelerating the development of new treatments for various diseases.
How similar studies have performed: Other research has shown success in automating NMR processes, indicating that this approach has potential for significant advancements in the field.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEE, WOONGHEE — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: LEE, WOONGHEE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.