Improving neurosurgery techniques for treating dementia and movement disorders
Imaging, Guidance, and QA for Emerging High-Precision Neurosurgical Techniques
['FUNDING_U01'] · JOHNS HOPKINS UNIVERSITY · NIH-10673990
This study is working on new ways to help people with movement disorders and dementia, like Alzheimer's, by improving brain surgery techniques to make sure treatments are more precise and safer.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10673990 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced neurosurgical techniques to treat various movement disorders and dementia, including Alzheimer's disease. It aims to enhance the precision of deep-brain stimulation (DBS) by using innovative electrode stimulators that are delivered to specific brain targets. The project will improve intraoperative imaging and navigation methods to ensure accurate placement of these stimulators, which is crucial for maximizing treatment effectiveness and minimizing risks. By addressing the challenges of brain shift and cerebrospinal fluid loss during surgery, this research seeks to refine the surgical approach for better patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or other movement disorders who may benefit from advanced neurosurgical interventions.
Not a fit: Patients with conditions unrelated to dementia or movement disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatments for patients suffering from dementia and movement disorders.
How similar studies have performed: Previous research has shown promising results with deep-brain stimulation techniques in Parkinson's disease, indicating potential for success in similar approaches for other conditions.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: UNERI, ALI — JOHNS HOPKINS UNIVERSITY
- Study coordinator: UNERI, ALI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease