Improving muscle regeneration in older adults
Control of Muscle Stem Cells to Enhance Regeneration
This study is looking at how getting older changes the muscle stem cells that help repair and grow muscles, and it aims to find ways to make these cells work better in older adults so they can recover and stay strong.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10987002 on NIH RePORTER |
What this research studies
This research investigates how aging affects muscle stem cells, which are crucial for muscle repair and regeneration. It focuses on understanding the differences between functional and dysfunctional muscle stem cells in older adults, using advanced single-cell technologies to analyze these cells. By identifying specific markers that distinguish healthy muscle stem cells, the research aims to develop strategies to enhance their function and improve muscle regeneration in the elderly.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing age-related muscle loss or sarcopenia.
Not a fit: Patients who are younger and do not have age-related muscle decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve muscle health and mobility in older adults, enhancing their quality of life.
How similar studies have performed: Other research has shown promise in targeting muscle stem cells for regeneration, indicating that this approach could be effective.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Blau, Helen M — Stanford University
- Study coordinator: Blau, Helen M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.