Improving muscle recovery in heart failure patients with protein supplements
A SkeleTal muscle Recovery Intervention with Dietary protein in Heart Failure (ASTRID-HF)
['FUNDING_R01'] · CLEVELAND CLINIC LERNER COM-CWRU · NIH-11145647
This study is looking at whether adding more protein to the diet can help people with heart failure build muscle and feel better, while also checking how it affects their overall health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CLEVELAND CLINIC LERNER COM-CWRU (nih funded) |
| Locations | 1 site (CLEVELAND, UNITED STATES) |
| Trial ID | NIH-11145647 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of oral protein supplementation on muscle mass and physical function in patients with heart failure with reduced ejection fraction (HFrEF). It aims to determine whether increasing dietary protein can reverse muscle loss and improve survival rates among these patients. The study will involve a randomized controlled trial to assess the effectiveness of this intervention, while also exploring the underlying biological mechanisms of muscle wasting in HFrEF. Patients will be monitored for changes in muscle mass and overall health outcomes over the course of the trial.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with heart failure with reduced ejection fraction.
Not a fit: Patients who do not have heart failure or those with other unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved muscle recovery and enhanced quality of life for patients suffering from heart failure.
How similar studies have performed: Previous research has shown promising results in muscle recovery interventions for heart failure patients, suggesting that this approach may be effective.
Where this research is happening
CLEVELAND, UNITED STATES
- CLEVELAND CLINIC LERNER COM-CWRU — CLEVELAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VEST, AMANDA RUTH — CLEVELAND CLINIC LERNER COM-CWRU
- Study coordinator: VEST, AMANDA RUTH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.