Improving muscle recovery after severe injuries
Official title: Regenerative and Rehabilitation Strategies to Reduce Inflammation Following Volumetric Muscle Loss Injury
Funded at University of Arkansas at Fayetteville · NIH-10974767 · Data updated 2026-11-12
This study is exploring new ways to help people recover from serious muscle injuries by using special materials and personalized exercise plans to reduce swelling and help muscles grow back stronger.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arkansas at Fayetteville NIH-funded |
| Lab location | 1 site (Fayetteville, United States) |
| Project start | August 8, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $434,793 |
| NIH project number | 1R15AR083119-01A1 |
| Project ID | NIH-10974767 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced significant muscle loss due to injury or surgery.
✕Less likely to help
Patients with minor muscle injuries or those who do not have volumetric muscle loss may not benefit from this research.
What this research studies
This research investigates new methods to enhance recovery from volumetric muscle loss (VML) injuries, which occur when a significant amount of muscle tissue is lost. The approach combines bioengineered scaffolds, like decellularized muscle tissue, with tailored exercise regimens to reduce inflammation and promote muscle regeneration. By determining the optimal exercise intensity and duration, the study aims to improve the effectiveness of these regenerative strategies. Patients may benefit from a comprehensive treatment plan that addresses both the biological and rehabilitative aspects of muscle recovery.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery outcomes for patients with severe muscle injuries, enhancing their ability to regain strength and function.
How similar studies have gone: Previous research has shown promise in using bioengineered scaffolds and exercise for muscle recovery, indicating that this combined approach may yield beneficial results.
Where this research is happening
-
University of Arkansas at Fayetteville
Fayetteville, United States Active
Researchers
- Principal investigator: Washington, Tyrone a — University of Arkansas at Fayetteville
- Study coordinator: Washington, Tyrone a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.