Improving muscle health and activity after sepsis with targeted nutrition
Targeted nutritional approach to restore muscle health and physical activity after sepsis
This study is looking at how certain nutritional supplements can help people recovering from sepsis regain their muscle strength and get back to being active, using pigs to learn more about the best ways to support recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas A&m University NIH-funded |
| Lab location | 1 site (College Station, United States) |
| Project ID | NIH-10780497 on NIH RePORTER |
What this research studies
This research investigates how specific nutritional interventions can help restore muscle health and physical activity in patients recovering from sepsis, a serious condition that can lead to long-term muscle weakness. The study will utilize animal models, particularly pigs, to understand the mechanisms of muscle breakdown and the effectiveness of a combined nutritional formulation that includes β-hydroxy β-methylbutyric acid and essential amino acids. By identifying the best nutritional strategies, the research aims to enhance rehabilitation outcomes for critically ill patients. The findings could lead to new nutritional guidelines for improving recovery after sepsis.
Who could benefit from this research
Good fit: Ideal candidates for this research are critically ill patients who have been diagnosed with sepsis and are experiencing muscle weakness and reduced physical activity.
Not a fit: Patients who are not critically ill or who have not experienced sepsis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve recovery and quality of life for patients who have experienced sepsis by restoring muscle function and increasing physical activity.
How similar studies have performed: Previous research has shown promise in using targeted nutritional approaches to improve recovery in critically ill patients, suggesting that this study builds on established concepts.
Where this research is happening
College Station, United States
- Texas A&m University — College Station, United States (Active)
Researchers
- Principal investigator: Deutz, Nicolaas E — Texas A&m University
- Study coordinator: Deutz, Nicolaas E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.