Improving MRI technology for studying brain diseases in small animals
Official title: Acquisition of a Bruker 11.7T/16cm Preclinical Scanner for Novel MRI/MRSI Studies
Funded at Yale University · NIH-10630511 · Data updated 2026-11-12
This study is working on improving MRI technology to take super-clear pictures of the brains of specially modified mice, which will help scientists learn more about brain diseases and how to treat them in people.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 15, 2023 |
| Project end | September 14, 2025 |
| Funding year | 2023 |
| Award (this year) | $2,000,000 |
| NIH project number | 1S10OD034234-01 |
| Project ID | NIH-10630511 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with genetic predispositions to brain disorders, as insights gained may directly inform future treatments.
✕Less likely to help
Patients with non-genetic brain disorders or those not involved in transgenic research may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing magnetic resonance imaging (MRI) capabilities to study transgenic rodents, which are vital for understanding brain diseases. By installing a state-of-the-art Bruker 11.7T preclinical scanner, the project aims to achieve ultrahigh resolution imaging that can distinguish fine anatomical structures in the brain. This advanced imaging technology will enable researchers to conduct detailed functional, structural, and metabolic studies, ultimately paving the way for translating findings to human health. The project will also replace an outdated system, ensuring continued support for ongoing research in the field.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in understanding and treating brain diseases by providing clearer insights into disease mechanisms.
How similar studies have gone: Other research has shown success with similar ultrahigh field MRI approaches, indicating a promising avenue for advancing brain imaging techniques.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Hyder, Dewan Syed Fahmeed — Yale University
- Study coordinator: Hyder, Dewan Syed Fahmeed
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.