Improving MRI techniques to evaluate abdominal aortic aneurysms
Advanced MRI Evaluation of Abdominal Aortic Aneurysms
This study is looking at new ways to use MRI scans to better understand and predict the growth and risk of rupture in abdominal aortic aneurysms (AAAs) in veterans, helping doctors keep a closer eye on those that might be more dangerous.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Affairs Med Ctr San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10738718 on NIH RePORTER |
What this research studies
This research focuses on enhancing MRI evaluation methods for abdominal aortic aneurysms (AAA), which are dangerous if they rupture. It aims to go beyond traditional measurements by using computational biomechanical modeling to assess wall stress, potentially offering better predictions of aneurysm growth and rupture. The study will explore the complex nature of AAA progression, including factors like inflammation and hemodynamics, to improve patient management. By identifying which small AAAs are at risk of rupture, the research could optimize surveillance strategies for affected veterans.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans diagnosed with small abdominal aortic aneurysms measuring less than 5.5 cm.
Not a fit: Patients with large abdominal aortic aneurysms or those who have already experienced a rupture may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate monitoring and management of abdominal aortic aneurysms, potentially reducing the risk of life-threatening ruptures.
How similar studies have performed: While abdominal aortic aneurysms have been extensively studied, the specific approach of using advanced MRI techniques and biomechanical modeling for risk assessment is relatively novel.
Where this research is happening
San Francisco, United States
- Veterans Affairs Med Ctr San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Mitsouras, Dimitrios — Veterans Affairs Med Ctr San Francisco
- Study coordinator: Mitsouras, Dimitrios
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.