Improving MRI techniques to better guide treatment for glioma patients
Official title: Development of multinuclear MRI for image guided therapy of glioma patients
Funded at Massachusetts General Hospital · NIH-10874753 · Data updated 2026-11-12
This study is working on improving MRI scans to get clearer pictures of gliomas, which are tough brain tumors, so that doctors can better plan surgeries and treatments, ultimately helping patients have better outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $682,470 |
| NIH project number | 5R01CA211080-07 |
| Project ID | NIH-10874753 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with gliomas who are scheduled for surgical intervention.
✕Less likely to help
Patients with non-glioma brain tumors or those who are not candidates for surgery may not benefit from this research.
What this research studies
This research focuses on enhancing MRI technology to provide clearer images of gliomas, which are aggressive brain tumors. By using advanced magnetic resonance spectroscopic imaging, the project aims to accurately map tumor boundaries, helping neurosurgeons perform more effective surgeries. The study also explores how metabolic changes in gliomas can inform new treatment strategies, potentially improving outcomes for patients undergoing chemotherapy and immunotherapy. The goal is to develop imaging methods that can lead to better surgical precision and treatment planning.
Why it matters
Potential benefit: If successful, this research could significantly improve surgical outcomes and survival rates for glioma patients.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for brain tumors, indicating potential success for this novel approach.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Andronesi, Ovidiu C — Massachusetts General Hospital
- Study coordinator: Andronesi, Ovidiu C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.