Improving MRI techniques for better diagnosis of multiple sclerosis
Official title: Quantification of Multi-Compartment T1 Relaxation and Magnetization Transfer in Biological Tissue: From Biophysics to Biomarkers for Multiple Sclerosis
Funded at New York University School of Medicine · NIH-10993185 · Data updated 2026-11-12
This study is working on improving MRI scans to make them more accurate for people with multiple sclerosis, so doctors can better understand the condition without taking too much time during the scan.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $570,975 |
| NIH project number | 5R01NS131948-02 |
| Project ID | NIH-10993185 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with multiple sclerosis or those exhibiting symptoms related to this condition.
✕Less likely to help
Patients with conditions unrelated to multiple sclerosis or those who do not undergo MRI scans may not benefit from this research.
What this research studies
This research focuses on enhancing quantitative MRI (qMRI) to provide more accurate and reliable imaging for conditions like multiple sclerosis. By addressing the variability in MRI measurements caused by oversimplified models, the project aims to improve the sensitivity and specificity of these scans. The researchers will develop a new approach that allows for more complex modeling of biological tissues while keeping scan times manageable for clinical use. This could lead to better diagnostic tools that can be routinely used in healthcare settings.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and monitoring of multiple sclerosis, ultimately improving patient care.
How similar studies have gone: Previous research has shown promise in improving MRI techniques, but this approach aims to address specific challenges that have not been fully explored.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Asslaender, Jakob — New York University School of Medicine
- Study coordinator: Asslaender, Jakob
Related research
Other NIH-funded projects on the same topics.
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More reliable MRI scans to detect and track Multiple Sclerosis
This project develops faster, more reliable MRI methods to better detect and track brain changes in people with multiple sclerosis.
-
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-
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-
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Astrocyte exosomes as aging biomarkers and drivers of MS progression
Researchers are testing a blood-based biomarker from astrocyte-like exosomes to understand why multiple sclerosis gets worse with age and to identify potential targets for treatment.
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Promoting brain repair in MS with a natural compound that nudges neural stem cells
A researcher is testing a natural-product–based compound that may help people with multiple sclerosis repair nerve damage by guiding brain stem cells to become neurons and myelin-producing cells.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.