Improving MRI techniques for assessing liver tumors
Official title: Rapid Motion-Robust and Easy-to-Use Dynamic Contrast-Enhanced MRI for Liver Perfusion Quantification
Funded at New York University School of Medicine · NIH-10869993 · Data updated 2026-11-12
This study is working on a quicker and more reliable MRI method to help doctors see blood flow in the liver for patients with liver cancer, making it easier and more comfortable for you to get important information about your condition without needing any invasive procedures.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | May 1, 2023 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $392,645 |
| NIH project number | 5R01EB030549-04 |
| Project ID | NIH-10869993 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with hepatocellular carcinoma or those at risk for liver cancer.
✕Less likely to help
Patients with liver conditions other than hepatocellular carcinoma or those who cannot undergo MRI due to contraindications may not benefit from this research.
What this research studies
This research aims to develop a new method for dynamic contrast-enhanced MRI (DCE-MRI) that is faster and more robust against motion, specifically for quantifying liver blood flow in patients with hepatocellular carcinoma (HCC). By using gadolinium-based contrast agents, the study seeks to enhance the ability to visualize and assess liver lesions non-invasively, providing critical information about tumor characteristics without the need for invasive biopsies. The new approach will address current limitations in MRI technology, such as slow imaging speeds and sensitivity to patient movement, making it easier for patients to undergo the procedure. Ultimately, this could lead to better diagnosis and treatment planning for liver cancer patients.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely assessments of liver tumors, improving treatment outcomes for patients with hepatocellular carcinoma.
How similar studies have gone: Previous research has shown promise in enhancing MRI techniques for liver assessment, indicating that this approach could build on existing knowledge and potentially lead to significant advancements.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Feng, Li — New York University School of Medicine
- Study coordinator: Feng, Li
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.