Improving MRI scans for children with epilepsy
Motion and Distortion Robust Diffusion Weighted Imaging Sequences for Pediatric Patients
This study is working on improving brain scans for kids with hard-to-treat epilepsy, making it easier to get clear images even if they move during the scan, so doctors can plan surgery better and help them feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10754863 on NIH RePORTER |
What this research studies
This research focuses on enhancing diffusion MRI techniques to better map critical brain regions in pediatric patients suffering from drug-resistant epilepsy. By addressing the challenges posed by head motion during scans, the study aims to develop a dual-echo EPI sequence that can correct motion-related distortions. This approach will allow for more accurate pre-surgical planning, helping to maximize the removal of epileptic foci while minimizing damage to surrounding brain areas. The research is particularly important for children who may struggle to remain still during imaging procedures.
Who could benefit from this research
Good fit: Ideal candidates for this research are pediatric patients with drug-resistant epilepsy who require surgical intervention.
Not a fit: Patients who do not have epilepsy or those whose seizures are well-controlled with medication may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective surgical outcomes for children with epilepsy by improving the accuracy of brain mapping prior to surgery.
How similar studies have performed: Previous research has shown promise in improving MRI techniques for pediatric populations, indicating that this approach could yield significant advancements.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Afacan, Onur — Boston Children's Hospital
- Study coordinator: Afacan, Onur
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.