Improving MRI mapping of brain temperature
Synergistic Advancements in MR Thermometry and Predictive Thermal Modeling Towards Improved Characterization of Human Brain Temperature
Using improved MRI scans and computer models to create accurate, noninvasive maps of brain temperature for people with brain injury.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11194258 on NIH RePORTER |
What this research studies
I want doctors to be able to see my brain temperature without putting probes into my head. This project combines advanced MRI thermometry techniques with predictive computer models that simulate how heat moves through brain tissue and blood vessels. Researchers will refine the MRI methods and models using empirical data to reduce errors from tissue differences and vascular effects. The team aims to produce reliable, whole-brain temperature images that could be used in clinical care after stroke or other acquired brain injuries.
Who could benefit from this research
Good fit: People with acquired brain injury or stroke, or those at risk of brain ischemia who can undergo MRI scans, are the most likely candidates for this work.
Not a fit: Individuals who cannot have MRI (for example due to incompatible implants or severe claustrophobia) or those without brain-temperature-related conditions may not benefit directly.
Why it matters
Potential benefit: If successful, this could allow safe, noninvasive monitoring of brain temperature to guide treatments and improve recovery after brain injury or stroke.
How similar studies have performed: MR-based brain thermometry has been demonstrated in research settings but has mostly produced relative, error-prone estimates, so this work builds on prior methods to improve accuracy and clinical reliability.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Fleischer, Candace C. — Emory University
- Study coordinator: Fleischer, Candace C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.