Improving MRI imaging of low oxygen levels in tumors
Outer sphere tuning of a Eu(II)-containing contrast agent for imaging hypoxia via MRI
This study is testing a new type of dye for MRI scans that helps doctors see low-oxygen areas in tumors more clearly, which could lead to better diagnosis and treatment for patients with cancer.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project ID | NIH-10995737 on NIH RePORTER |
What this research studies
This research focuses on developing a new contrast agent that can enhance MRI imaging of hypoxic (low oxygen) areas in tumors. By using a special compound containing europium, the team aims to create clearer images that can help identify aggressive disease states and improve treatment planning. The project seeks to overcome the challenge of the contrast agent's short lifespan in the body, allowing for better systemic delivery and imaging of hypoxic regions across various diseases. Patients may benefit from more accurate diagnostics and tailored therapies based on their tumor's oxygen levels.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with tumors that are suspected to be hypoxic or resistant to standard treatments.
Not a fit: Patients with non-tumor-related conditions or those whose tumors are not hypoxic may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more precise imaging of tumors, allowing for better diagnosis and treatment strategies for patients with hypoxic tumors.
How similar studies have performed: Previous research has shown promise in using europium-based contrast agents for imaging, indicating potential success for this novel approach.
Where this research is happening
Detroit, United States
- Wayne State University — Detroit, United States (Active)
Researchers
- Principal investigator: Batchev, Andrea — Wayne State University
- Study coordinator: Batchev, Andrea
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.