NIH-funded research R01 grant

Improving MRI imaging for better brain tumor detection and treatment

Official title: Integrated, dynamic B0 and flip-angle shimming using multi-coil shim arrays

Funded at Massachusetts General Hospital · NIH-11042751 · Data updated 2026-11-12

This study is working on making MRI images of the brain clearer and more accurate, especially for people with brain tumors or multiple sclerosis, so that doctors can provide better diagnoses and treatments.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startMarch 1, 2024
Project endAugust 31, 2028
Funding year2025
Award (this year)$655,298
NIH project number5R01EB034274-02
Project IDNIH-11042751 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with brain tumors, multiple sclerosis, or other neurological disorders requiring advanced imaging techniques.

Less likely to help

Patients with conditions unrelated to brain imaging or those who do not require MRI scans may not benefit from this research.

What this research studies

This research focuses on enhancing the quality of MRI images used for diagnosing and treating brain conditions, particularly brain tumors and multiple sclerosis. It aims to address the challenges posed by inhomogeneous magnetic fields in high-resolution 7T MRI systems, which can degrade image quality. By utilizing advanced technologies like multi-coil shim arrays and parallel transmission, the project seeks to improve the accuracy and reliability of MRI scans, making them more effective for clinical use. Patients may benefit from more precise imaging that can lead to better treatment outcomes.

Why it matters

Potential benefit: If successful, this research could lead to significantly improved MRI imaging techniques that enhance the diagnosis and treatment of brain tumors and other neurological conditions.

How similar studies have gone: Previous research has shown promise in improving MRI imaging techniques, but this approach utilizing dynamic shimming and multi-coil arrays is relatively novel.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Guerin, Bastien — Massachusetts General Hospital
  • Study coordinator: Guerin, Bastien

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.