Improving MRI for detecting and assessing bone lesions from cancers
Official title: Next-Generation Whole-Body MRI for Detection and Assessment of Therapy Response in Bone Lesions
Funded at Mayo Clinic Rochester · NIH-11141500 · Data updated 2026-11-12
This study is testing a new MRI technique that helps doctors find and see bone tumors from cancers like breast and prostate cancer more clearly, making the scans quicker and more comfortable for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $510,954 |
| NIH project number | 7R01CA283663-02 |
| Project ID | NIH-11141500 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients diagnosed with solid tumors such as breast, prostate, or kidney cancers, as well as those with multiple myeloma or other bone-related pathologies.
✕Less likely to help
Patients with non-cancerous bone conditions or those who do not have bone lesions may not benefit from this research.
What this research studies
This research focuses on enhancing whole-body MRI techniques to better detect and assess bone lesions caused by various cancers, including breast and prostate cancer. The innovative approach, called Dual-Echo T2-weighted acquisition for Enhanced Conspicuity of Tumors (DETECT), aims to improve the visualization of these lesions while reducing scan times and discomfort for patients. By separating fat and fluid signals, this method enhances lesion detection significantly compared to traditional MRI methods. The goal is to provide earlier and more accurate diagnoses, ultimately improving patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better management of bone lesions, significantly improving the quality of life for patients with cancer.
How similar studies have gone: Previous research has shown promising results with advanced MRI techniques, indicating potential for success with this novel approach.
Where this research is happening
-
Mayo Clinic Rochester
Rochester, United States Active
Researchers
- Principal investigator: Madhuranthakam, Ananth J — Mayo Clinic Rochester
- Study coordinator: Madhuranthakam, Ananth J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.