Improving MRI Accuracy for Cancer Treatment Decisions
Correction of Diffusion Gradient Bias in Quantitative Diffusivity Metrics for MultiPlatform Clinical Oncology Trials
This work helps make sure that MRI scans used in cancer care give clear and reliable information, especially for patients with breast cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11127681 on NIH RePORTER |
What this research studies
When patients have MRI scans to check on their cancer, especially in large clinical trials, sometimes the equipment can cause small errors in the images. These errors can make it harder for doctors to understand how well a treatment is working or to accurately characterize tissue. This project developed tools to fix these errors, making MRI results more consistent and trustworthy across different hospitals and machines. The goal is to ensure that the information from your MRI helps your care team make the best decisions for you.
Who could benefit from this research
Good fit: This work indirectly benefits patients undergoing quantitative diffusion imaging (DWI) as part of multi-center clinical oncology trials, particularly those with breast cancer.
Not a fit: Patients not undergoing quantitative diffusion imaging for cancer treatment assessment would not directly benefit from this specific technical improvement.
Why it matters
Potential benefit: If successful, this work will lead to more accurate and consistent MRI results for cancer patients, helping doctors make better treatment decisions.
How similar studies have performed: This project builds on previous discoveries of systematic bias in diffusion imaging and has already demonstrated feasibility for retrospective correction in a breast cancer imaging trial.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Malyarenko, Dariya I. — University of Michigan at Ann Arbor
- Study coordinator: Malyarenko, Dariya I.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.