Improving movement and cognitive functions in Parkinson's disease

Optimizing pallidofugal modulation of midbrain and thalamic nuclei for treating cognitive-motor signs of Parkinson's disease

['FUNDING_OTHER'] · UNIVERSITY OF MINNESOTA · NIH-10930886

This study is looking at how certain parts of the brain that help with movement and thinking are impacted by Parkinson's disease, and it hopes to find new ways to improve treatment for patients dealing with walking difficulties and cognitive issues.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MINNESOTA (nih funded)
Locations1 site (MINNEAPOLIS, UNITED STATES)
Trial IDNIH-10930886 on ClinicalTrials.gov

What this research studies

This research investigates how specific brain regions involved in movement and cognition are affected in Parkinson's disease. By using advanced techniques like deep brain stimulation and wireless recordings, the study aims to understand the connections between these brain areas and how they contribute to symptoms like gait dysfunction and cognitive challenges. Patients may benefit from insights that could lead to better treatment strategies for managing their symptoms.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who experience gait dysfunction and cognitive difficulties.

Not a fit: Patients with Parkinson's disease who do not exhibit significant cognitive or motor symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for cognitive and motor symptoms in patients with Parkinson's disease.

How similar studies have performed: Previous research has shown that deep brain stimulation can effectively improve motor symptoms in Parkinson's disease, suggesting potential for success in this related approach.

Where this research is happening

MINNEAPOLIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.