Improving mouse models to better understand and treat melanoma
Official title: BLRD Research Career Scientist Award Application
Funded at VA New Jersey Health Care System · NIH-11101235 · Data updated 2026-11-12
This study is working on improving mouse models of melanoma that has spread to the brain, so we can better understand the disease and develop new treatments that really help people with advanced melanoma.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA New Jersey Health Care System NIH-funded |
| Lab location | 1 site (East Orange, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| NIH project number | 5IK6BX006319-03 |
| Project ID | NIH-11101235 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with melanoma, especially those with late-stage disease or brain metastases.
✕Less likely to help
Patients with early-stage melanoma or those not diagnosed with melanoma may not receive any benefit from this research.
What this research studies
This research focuses on enhancing mouse models that mimic human melanoma, particularly those with brain metastases, to improve the translation of basic science discoveries into effective clinical therapies. By refining these models, the research aims to provide consistent and reliable information that can better meet the needs of patients suffering from melanoma. The study builds on previous findings related to altered metabolisms in melanoma development and seeks to leverage innovative approaches to advance treatment options for late-stage melanoma.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with melanoma, particularly those with advanced disease.
How similar studies have gone: Other research has shown success in using refined animal models to improve the understanding and treatment of various cancers, indicating that this approach has potential.
Where this research is happening
-
VA New Jersey Health Care System
East Orange, United States Active
Researchers
- Principal investigator: Chen, Suzie — VA New Jersey Health Care System
- Study coordinator: Chen, Suzie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.