Improving models for studying head and neck cancer treatments
Improving the translational value of head and neck cancer patient-in-mouse models
['FUNDING_R37'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-10977490
This study is looking at how to improve models that use patient tumor samples to better understand head and neck cancer, so that doctors can find more effective treatments for patients like you.
Quick facts
| Phase | ['FUNDING_R37'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-10977490 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the effectiveness of patient-derived models used to study head and neck cancer. By using tumor samples from patients, the researchers aim to understand how different methods of implanting these tumors in mice affect the outcomes of cancer treatment studies. The project will investigate factors such as the location of tumor implantation and how the models evolve over time, with the goal of creating more accurate and predictive models that can better inform patient care. Ultimately, the research seeks to bridge the gap between laboratory findings and clinical applications for head and neck cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with head and neck cancer who are undergoing surgical procedures to remove tumors.
Not a fit: Patients with head and neck cancer who are not undergoing surgery or who are in advanced stages of the disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for head and neck cancer patients by improving the relevance of preclinical models.
How similar studies have performed: Previous research has shown that improving the methodologies of patient-derived models can enhance the translational value of findings, indicating potential success for this approach.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KIMPLE, RANDALL J. — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: KIMPLE, RANDALL J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.