Improving mobility for patients with peripheral artery disease after surgery
Official title: 2/2 Improving Mobility After Revascularization in Peripheral Artery Disease: The IMPACT PAD Trial
Funded at Wake Forest University Health Sciences · NIH-10885665 · Data updated 2026-11-12
This study is looking to help people with peripheral artery disease move better after their revascularization surgery, and it will involve a lot of participants to find the best ways to improve their mobility and quality of life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project start | September 17, 2024 |
| Project end | August 31, 2031 |
| Funding year | 2024 |
| Award (this year) | $699,396 |
| NIH project number | 1U24HL169563-01A1 |
| Project ID | NIH-10885665 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with peripheral artery disease who are scheduled to undergo revascularization surgery.
✕Less likely to help
Patients who do not have peripheral artery disease or are not undergoing revascularization surgery may not benefit from this research.
What this research studies
This research focuses on enhancing the ability of patients with peripheral artery disease to move better after they undergo revascularization surgery. The study will involve a large group of participants and will utilize a data coordinating center to manage and analyze the data collected throughout the trial. Patients will be monitored closely to ensure their safety and adherence to the treatment protocols, with the goal of improving their mobility and overall quality of life. The trial aims to implement effective strategies based on previous successful studies.
Why it matters
Potential benefit: If successful, this research could significantly improve mobility and quality of life for patients recovering from peripheral artery disease surgery.
How similar studies have gone: Previous studies have shown success in improving patient outcomes through similar approaches in managing recovery after surgical interventions.
Where this research is happening
-
Wake Forest University Health Sciences
Winston-Salem, United States Active
Researchers
- Principal investigator: Ambrosius, Walter T — Wake Forest University Health Sciences
- Study coordinator: Ambrosius, Walter T
Related research
Other NIH-funded projects on the same topics.
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Low-dose colchicine to reduce vascular risk in people with peripheral artery disease
This project tests whether taking a low-dose anti-inflammatory drug (colchicine) daily can lower heart and limb-related risks for adults with peripheral artery disease.
-
Gamified home walking program to help seniors with peripheral artery disease improve walking and quality of life
A program uses game elements on wearable devices to help people 65+ with peripheral artery disease walk more at home and feel better.
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Fatty clues in leg arteries: how fat burning in mitochondria affects PAD and muscle health
This project looks at how fat metabolism in leg muscles relates to weakness and tissue damage in people with peripheral artery disease and aims to find new ways to help them.
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Enhancing muscle energy to help leg function in PAD
A study to boost how muscle mitochondria work in people with peripheral artery disease to improve walking and leg function.
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Low-dose colchicine for people with peripheral artery disease to reduce heart and limb risks
A large international study will test whether a low daily dose of colchicine can lower heart and limb complications for people with peripheral artery disease.
-
Low-dose colchicine for reducing vascular risk in people with PAD
A large international study will test whether a daily low dose of colchicine can lower heart and limb-related risks for people with peripheral artery disease.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.