Improving methods to identify extreme health outcomes in patient data

Improving statistical inference when interest focuses on the identification of extreme random effects in clustered data

NIH-funded research University of California, San Francisco · NIH-10665751

This study is working on new ways to help doctors spot patients who might suddenly get worse or hospitals that aren't doing well, so they can provide better care and support, and it will also include easy-to-use software to make these tools accessible for healthcare teams.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10665751 on NIH RePORTER

What this research studies

This research focuses on enhancing statistical models that predict extreme health outcomes for patients, such as rapid declines in health or poor hospital performance. By developing new methods to identify these outliers, the research aims to provide healthcare professionals with better tools for evaluating patient and hospital performance. The approach includes theoretical calculations, simulations, and real-world examples to ensure the methods are robust and effective. Additionally, user-friendly software will be created to help implement these new techniques in clinical settings.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients with complex health conditions who may experience rapid changes in their health status.

Not a fit: Patients with stable health conditions or those not part of clustered data analyses may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved identification of patients at risk for severe health declines, allowing for timely interventions.

How similar studies have performed: Previous research has shown that advanced statistical methods can significantly improve the identification of outlier health outcomes, suggesting that this approach has the potential for success.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.