Improving methods to analyze metabolites in biological systems
Advanced NMR, computational, and hybrid methods for metabolomics
This study is working on better ways to identify and measure tiny molecules in your body that can help doctors understand your health, especially in conditions like cancer, so that patients can get improved tests and treatments based on their unique metabolic profiles.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-11085996 on NIH RePORTER |
What this research studies
This research focuses on enhancing the analysis of metabolites, which are small molecules that play crucial roles in biological systems. By integrating advanced nuclear magnetic resonance (NMR) techniques with computational methods and mass spectrometry, the project aims to develop new tools for identifying and quantifying metabolites in complex samples like blood and cancer tissues. Patients may benefit from improved diagnostic methods and treatments based on a better understanding of their metabolic profiles. The research also includes creating user-friendly databases and web tools to facilitate the analysis of metabolomics data.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with metabolic disorders or cancers who may benefit from advanced diagnostic techniques.
Not a fit: Patients with conditions unrelated to metabolism or those not requiring metabolic profiling may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and personalized treatment options for patients with various diseases, including cancers.
How similar studies have performed: Previous research has shown promising results in metabolomics, indicating that this approach has the potential to significantly advance our understanding of biological systems.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Bruschweiler, Rafael — Ohio State University
- Study coordinator: Bruschweiler, Rafael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.