Improving methadone access for opioid use disorder treatment

Leveraging regulatory flexibility for methadone take-home dosing to improve retention in treatment for opioid use disorder: A stepped-wedge randomized trial to facilitate clinic level changes

NIH-funded research New York University School of Medicine · NIH-10913634

This study is looking at how new rules during the COVID-19 pandemic can make it easier for people with opioid use disorder to get take-home methadone, so they don’t have to visit clinics as often, which could help them stick with their treatment and feel better overall, especially for those in Black/African American and Latinx communities.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNew York University School of Medicine NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10913634 on NIH RePORTER

What this research studies

This research investigates how changes in regulations during the COVID-19 pandemic can enhance access to take-home methadone for individuals with opioid use disorder (OUD). By allowing patients to take methadone home instead of requiring frequent clinic visits, the study aims to improve retention in treatment and overall quality of life. The approach involves a stepped-wedge randomized trial, where clinics will gradually implement these changes and assess their impact on patient outcomes. The research particularly focuses on addressing disparities faced by Black/African American and Latinx communities in accessing effective treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with opioid use disorder who are currently receiving or seeking treatment at opioid treatment programs.

Not a fit: Patients who do not have opioid use disorder or those who are not engaged in treatment programs may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved retention in treatment for opioid use disorder, ultimately saving lives and enhancing the quality of life for patients.

How similar studies have performed: Other research has shown that more flexible take-home dosing can improve treatment retention and outcomes, suggesting that this approach may be effective.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.