NIH-funded research U01 cooperative agreement

Improving mental health understanding in young adults using advanced models

Official title: JASPer-MH: Jointly Assessed Scalable Phenotypes for Mental Health

Funded at Massachusetts General Hospital · NIH-11092268 · Data updated 2026-11-12

This study is looking to improve how we understand and spot mental health issues in teens and young adults early on, using advanced technology to help identify those at risk so they can get the support they need.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startMay 20, 2024
Project endFebruary 28, 2029
Funding year2025
Award (this year)$1,792,896
NIH project number5U01MH136059-02
Project IDNIH-11092268 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation are adolescents and young adults aged 12 to 20 who may be experiencing mental health challenges.

Less likely to help

Patients outside the age range of 12 to 20 or those with established severe mental health conditions may not benefit from this research.

What this research studies

This research focuses on enhancing the understanding of mental health trajectories in adolescents and young adults by utilizing advanced electronic health record (EHR) data and artificial intelligence models. The goal is to develop more accurate risk stratification models that can identify mental health issues early, allowing for timely interventions. By integrating cognitive tasks and dimensional traits into the analysis, the research aims to capture a more comprehensive picture of mental health beyond traditional diagnostic codes. This approach seeks to address the public health crisis of mental illness in youth during critical developmental stages.

Why it matters

Potential benefit: If successful, this research could lead to earlier identification and more effective interventions for mental health issues in young adults.

How similar studies have gone: Previous research has shown promise in using electronic health records and cognitive assessments for improving mental health predictions, indicating a potential for success in this novel approach.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Perlis, Roy H. — Massachusetts General Hospital
  • Study coordinator: Perlis, Roy H.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.