Improving mental health treatment for people with HIV using advanced statistical methods.
Bayesian Methods for Optimizing Combination Antiretroviral Therapy for Mentalhealth in People with HIV
['FUNDING_R01'] · JOHNS HOPKINS UNIVERSITY · NIH-11082364
This study is looking at how to improve mental health for people living with HIV by finding the best combinations of medications that not only help manage the virus but also reduce feelings of depression and other mental health issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11082364 on ClinicalTrials.gov |
What this research studies
This research focuses on optimizing combination antiretroviral therapy (cART) to improve mental health outcomes for individuals living with HIV. It aims to understand how cART can lead to mental health issues, particularly depression, and how to tailor treatments to minimize these adverse effects. By analyzing large public datasets, the study will develop sophisticated statistical models to identify the best drug combinations for individual patients, taking into account their unique treatment histories and clinical characteristics. This approach seeks to enhance long-term mental health and overall well-being for people with HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are currently undergoing or considering combination antiretroviral therapy.
Not a fit: Patients who are not living with HIV or those who are not on antiretroviral therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options that improve mental health outcomes for people living with HIV.
How similar studies have performed: Previous research has shown promise in using advanced statistical methods to optimize treatment regimens, indicating that this approach could yield significant benefits.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: XU, YANXUN — JOHNS HOPKINS UNIVERSITY
- Study coordinator: XU, YANXUN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus