Improving mental health for orphans and vulnerable children in South Africa

MISC-CBO: A cluster randomized control trial to improve the mental health of OVC in South Africa

NIH-funded research University of Houston · NIH-10876355

This study is looking at how a special program can help caregivers support the mental health of orphans and vulnerable children in South Africa, especially those aged 7 to 11, by improving their interactions through video feedback.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Houston NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-10876355 on NIH RePORTER

What this research studies

This research focuses on enhancing the mental health of orphans and vulnerable children (OVC) in South Africa through a community-based intervention. It utilizes a program called Mediational Intervention for Sensitizing Caregivers (MISC-CBO), which trains community careworkers to better support children's mental health needs. The intervention involves video feedback and aims to improve caregiver-child interactions, particularly for children aged 7-11 years. By conducting a cluster randomized trial, the research will assess the effectiveness of this approach and its potential for broader implementation.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 7-11 years who are orphans or considered vulnerable due to socio-economic factors.

Not a fit: Children outside the age range of 7-11 years or those not classified as orphans or vulnerable may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the mental health outcomes of orphans and vulnerable children in South Africa.

How similar studies have performed: Previous research has shown success with similar community-based interventions aimed at improving mental health in vulnerable populations.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.