Improving mental health care for patients with psychosis in Malawi through community support.

Enhancing post-acute mental health outcomes for patients with psychosis in Malawi through nurse-delivered community-based rehabilitation: The ENHANCE Pilot Trial

NIH-funded research Univ of North Carolina Chapel Hill · NIH-10847412

This study is looking at how a special program run by nurses can help people with psychosis in Malawi feel better and get the support they need in their communities, rather than just in hospitals.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-10847412 on NIH RePORTER

What this research studies

This research focuses on enhancing the mental health outcomes of individuals with psychosis in Malawi by implementing a community-based rehabilitation program delivered by nurses. The approach emphasizes long-term outpatient care rather than just acute inpatient treatment, addressing the unique challenges faced by patients in low-resource settings. By integrating community support, the program aims to reduce stigma, improve medication adherence, and provide ongoing assistance to patients and their families. The methodology involves training nurses to deliver tailored rehabilitation services that meet the specific needs of patients in their communities.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with psychotic disorders who are in need of long-term outpatient care and support.

Not a fit: Patients with acute psychotic episodes requiring immediate hospitalization may not benefit from this community-based approach.

Why it matters

Potential benefit: If successful, this research could significantly improve the quality of life and functionality for patients with psychosis in Malawi.

How similar studies have performed: Previous research has shown that community-based rehabilitation can effectively improve outcomes for individuals with various disabilities, suggesting potential success for this novel approach in mental health care.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.