Improving memory through sleep spindle measurements
Optimizing sleep spindle measurements as translational assays of memory consolidation
This study is looking at how certain brain waves during sleep, called sleep spindles, might help improve memory for people with memory problems, especially those with Alzheimer's disease, and aims to find ways to boost these brain waves to support better memory.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10791859 on NIH RePORTER |
What this research studies
This research investigates how sleep spindles, which are brain wave patterns during sleep, can be used to enhance memory consolidation in individuals with memory impairments, particularly those with Alzheimer's disease. By studying both humans and animal models, the research aims to understand the relationship between sleep spindles and other brain oscillations that are crucial for memory. The goal is to develop interventions that can effectively increase sleep spindles and improve memory function, potentially leading to new treatments for cognitive disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related memory impairments.
Not a fit: Patients without memory impairments or those not diagnosed with cognitive disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance memory function in patients with Alzheimer's disease and other cognitive disorders.
How similar studies have performed: Previous studies have shown promising results in using sleep spindles to improve memory, indicating that this approach has potential for success.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Manoach, Dara S — Massachusetts General Hospital
- Study coordinator: Manoach, Dara S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.