NIH-funded research NIH-funded research

Improving medication safety for older adults with Alzheimer's and related dementias

Official title: The U.S. Deprescribing Research Network

Funded at Northern California Institute/res/edu · NIH-11141896 · Data updated 2026-11-12

This study is all about finding better ways to help older adults with Alzheimer's and related dementias safely reduce or stop medications that they might not need, so they can feel better and avoid any harmful side effects.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNorthern California Institute/res/edu
NIH-funded
Lab location1 site (San Francisco, United States)
Project startAugust 1, 2024
Project endApril 30, 2029
Funding year2025
Award (this year)$809,610
NIH project number5R33AG086944-02
Project IDNIH-11141896 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults diagnosed with Alzheimer's disease or related dementias who are currently taking multiple medications.

Less likely to help

Patients who are not diagnosed with Alzheimer's disease or related dementias, or those who are not on multiple medications, may not benefit from this research.

What this research studies

This research focuses on deprescribing, which is the process of safely reducing or stopping medications that may be unnecessary or harmful for older adults, particularly those with Alzheimer's disease and related dementias. The project aims to develop new methods and collaborations to enhance the understanding and implementation of deprescribing practices. By engaging a network of interprofessional investigators, the research seeks to create educational programs and pilot projects that will lead to better medication management for vulnerable older adults. The ultimate goal is to improve patient outcomes by minimizing adverse effects from inappropriate medication use.

Why it matters

Potential benefit: If successful, this research could lead to safer medication practices and improved quality of life for older adults with Alzheimer's and related dementias.

How similar studies have gone: Previous research has shown promise in deprescribing practices, indicating that this approach could lead to significant improvements in patient care.

Where this research is happening

  • Northern California Institute/res/edu
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Steinman, Michael a. — Northern California Institute/res/edu
  • Study coordinator: Steinman, Michael a.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.