Improving medication management for older adults with Alzheimer's disease and related dementias

eAlign: A Patient Portal-based Intervention to Align Medications with What Matters Most

NIH-funded research Johns Hopkins University · NIH-10908740

This study is all about helping older adults with Alzheimer's and similar conditions manage their medications better by involving their caregivers, giving them helpful resources, and teaching them about non-drug options to improve behavior, so everyone can work together to make medication choices that fit the patient's needs and goals.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10908740 on NIH RePORTER

What this research studies

This research focuses on helping older adults with Alzheimer's disease and related dementias (ADRD) manage their medications more effectively. It aims to engage care partners through a patient portal, providing them with educational resources to support the deprescribing of potentially harmful medications. The intervention includes training for care partners on non-drug treatments for behavioral symptoms and aims to reduce the overall medication burden on patients. By refining communication between patients, care partners, and healthcare providers, the project seeks to align medication decisions with the patients' personal goals.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults diagnosed with Alzheimer's disease or related dementias who are currently taking multiple medications.

Not a fit: Patients who are not diagnosed with Alzheimer's disease or related dementias or those who are not on multiple medications may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer medication practices and improved quality of life for patients with Alzheimer's disease and related dementias.

How similar studies have performed: Previous research has shown that interventions aimed at deprescribing can improve outcomes for patients with dementia, indicating a promising approach.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer's disease and related dementiaAlzheimer's disease and related disordersAlzheimer's disease or a related dementiaAlzheimer's disease or a related disorderAlzheimer's disease or related dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.