Improving medication management for children with complex health needs

Optimizing the Clinical Management of Polypharmacy for Children with Medical Complexity

NIH-funded research University of Colorado Denver · NIH-11000812

This study is looking at how a special program led by pharmacists can help kids who take multiple medications stay healthier and avoid trips to the emergency room, and it will compare this new approach to the usual care they receive.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-11000812 on NIH RePORTER

What this research studies

This research focuses on enhancing the management of multiple medications in children with medical complexity, who often require five or more concurrent medications. It aims to address medication-related problems that can lead to emergency visits or hospitalizations by implementing a pharmacist-led Pediatric Medication Therapy Management (pMTM) intervention. The study will compare this new approach to standard care to see if it effectively reduces medication-related issues and improves overall health outcomes for these children. By utilizing a randomized controlled trial, the research seeks to provide a structured method for better managing polypharmacy in pediatric patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are children with medical complexity who are currently prescribed five or more medications.

Not a fit: Patients who are not on multiple medications or do not have complex medical needs may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective medication management for children with complex health needs, reducing hospital visits and improving their quality of life.

How similar studies have performed: Previous research has shown that pharmacist-led medication management can be effective in adult and geriatric populations, suggesting potential success in pediatric applications.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.