Improving medication care for children with complex medical needs
Optimizing the Clinical Management of Polypharmacy for Children with Medical Complexity
['FUNDING_R01'] · UNIVERSITY OF COLORADO DENVER · NIH-11247581
A pharmacist-led medication review aims to reduce medication problems for children with complex medical needs who take many medicines.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-11247581 on ClinicalTrials.gov |
What this research studies
You and your child would be invited to a program where a pharmacist reviews all medicines using a structured Pediatric Medication Therapy Management (pMTM) approach. Children are randomly assigned to receive this pharmacist-led review or usual care, and the team follows families over time to track medication-related problems, symptom burden, and emergency visits or hospital stays. The intervention combines clinical visits, chart review, and pharmacist recommendations shared with the medical team and caregivers. The study also looks at how well pMTM can be put into routine pediatric care.
Who could benefit from this research
Good fit: Children with medical complexity who take five or more medications at the same time, along with their caregivers, are the ideal participants.
Not a fit: Children who are not on multiple medications, are clinically stable on few medicines, or adults are unlikely to benefit from this pediatric-focused program.
Why it matters
Potential benefit: If successful, this approach could reduce harmful medication problems, improve symptoms, and lower emergency visits and hospitalizations for children with complex medical needs.
How similar studies have performed: Pharmacist-led medication therapy management has improved medication safety in adults and older adults, but it has not been widely tested in children with medical complexity.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FEINSTEIN, JAMES A — UNIVERSITY OF COLORADO DENVER
- Study coordinator: FEINSTEIN, JAMES A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.