Improving medication adherence in adolescents with sickle cell disease using a mobile app

An mHealth Strategy to Improve Medication Adherence in Adolescents with Sickle Cell Disease

NIH-funded research Lurie Children's Hospital of Chicago · NIH-10799704

This study is testing a helpful mobile app called HU-Go to see if it can make it easier for teens and young adults with sickle cell disease to take their important medication, hydroxyurea, and how that might improve their overall health and well-being.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLurie Children's Hospital of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10799704 on NIH RePORTER

What this research studies

This research focuses on enhancing medication adherence among adolescents and young adults with sickle cell disease through a mobile health application called HU-Go. The study aims to understand how adherence to hydroxyurea, a critical medication, affects health-related quality of life over time. Researchers will refine the app based on user feedback and assess its usability and effectiveness in helping patients manage their condition. By engaging patients in their care, the project seeks to improve health outcomes and reduce healthcare costs.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents and young adults diagnosed with sickle cell disease who are prescribed hydroxyurea.

Not a fit: Patients who are not diagnosed with sickle cell disease or those who are not prescribed hydroxyurea may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes and quality of life for adolescents with sickle cell disease by enhancing their medication adherence.

How similar studies have performed: Previous research has shown that mobile health interventions can successfully improve medication adherence in various chronic conditions, suggesting a promising approach for this population.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Hb SS diseaseHbSS diseaseHemoglobin S DiseaseHemoglobin sickle cell diseaseHemoglobin sickle cell disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.