Improving medication adherence in adolescents after liver transplant
Improving Medication Adherence in adolescents who had a Liver Transplant: iMALT
This study is all about helping teenagers who have had a liver transplant remember to take their important medicine to keep their new liver healthy, using friendly phone calls and video chats to support them along the way.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10891339 on NIH RePORTER |
What this research studies
This research focuses on enhancing the adherence of adolescent liver transplant recipients to their immunosuppressant medication regimens, which is crucial for preventing organ rejection. By utilizing a tailored telemetric intervention, the study aims to engage patients through remote communication methods such as phone calls and video chats. The intervention will address psychological barriers to self-care and provide reminders and problem-solving strategies to improve medication adherence. Participants will be monitored using the Medication Level Variability Index (MLVI) to assess their adherence levels and adjust interventions accordingly.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents who have undergone a liver transplant and exhibit signs of nonadherence to their immunosuppressant medications.
Not a fit: Patients who are not adolescents or those who have not undergone a liver transplant may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of organ rejection in adolescent liver transplant recipients by improving their medication adherence.
How similar studies have performed: Previous research has shown that telemetric interventions can effectively improve medication adherence in various patient populations, suggesting a promising approach for this study.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Shemesh, Eyal — Icahn School of Medicine at Mount Sinai
- Study coordinator: Shemesh, Eyal
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.