Improving medication adherence for women with metastatic breast cancer

Improving medication adherence using a CONnected CUstomized Treatment Platform (CONCURxP)

NIH-funded research University of California-Irvine · NIH-10893604

This study is looking for ways to help women with hormone receptor-positive, HER2-negative metastatic breast cancer stick to their medication plans by using a special mobile app and smart pillbox, and it’s open to English- or Spanish-speaking women who have just started taking CDK4/6 inhibitors.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-10893604 on NIH RePORTER

What this research studies

This research investigates ways to enhance medication adherence among adult women diagnosed with hormone receptor-positive, HER2-negative metastatic breast cancer. It utilizes a personalized mobile health intervention called the CONnected CUstomized Treatment Platform (CONCURxP), which includes a smart pillbox to objectively track medication intake. Participants will be randomly assigned to receive either this innovative intervention or enhanced usual care, with the goal of improving adherence to complex medication regimens that are crucial for survival. The study will involve English- or Spanish-speaking women who have recently been prescribed CDK4/6 inhibitors.

Who could benefit from this research

Good fit: Ideal candidates for this research are adult women with hormone receptor-positive, HER2-negative metastatic breast cancer who have a new prescription for a CDK4/6 inhibitor and own a mobile phone capable of text messaging.

Not a fit: Patients who do not have access to a mobile phone or are not fluent in English or Spanish may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve medication adherence, leading to better health outcomes and increased survival rates for women with metastatic breast cancer.

How similar studies have performed: Previous research has shown promising results in improving medication adherence through mobile health interventions, indicating that this approach has potential for success.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast CancerCancer Treatment
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.